Combat obesity with data-driven medicine
MyPhenomeTM test utilizes your DNA to predict your response to weight loss interventions.
Know WHY you struggle with weight loss, so you know WHAT to do about it.
Request MyPhenome test from your health care provider.
For Healthcare Professionals
Explore the testing process and the science behind the MyPhenomeTM test.
For Patients
Learn how MyPhenomeTM test works and how it can accelerate your weight loss.
Data-driven precision medicine individualizes obesity treatment.
Leading physicians from Mayo Clinic, Drs. Andres Acosta and Michael Camilleri, studied nearly 1000 patients and found that obesity can be categorized as four different diseases requiring different treatments. We refer to these as obesity phenotypes: Hungry Brain, Hungry Gut, Emotional Hunger, and Slow Burn.1 Obesity phenotyping empowers providers to use precision medicine to individualize treatment, and was shown to double the amount of weight lost.
Acosta, A., Camilleri, M., Abu Dayyeh, B. (2021) Selection of Antiobesity Medications Based on Phenotypes Enhances Weight Loss: A Pragmatic Trial in an Obesity Clinic. Obesity, 29(4) 662-671. https://doi.org/10.1002/oby.23120.
Clinical Data
Access our clinical studies and papers on obesity phenotyping.
How it Works
DNA contributes 40-70% to body composition. Find out how to manage the effects of biology.
Partnerships
Join us in the quest to conquer obesity.
Manoel Galvao Neto, MD, MSc, FASGE, IFASMBS
Director of Bariatric Research, Orlando Health
Scientific Director of IRCAD
"For years, obesity care relied on observation, not precision. Dr. Andres Acosta and his team's research changed that, revealing distinct obesity subtypes defined by genetic, metabolic, and behavioral traits.
This led to MyPhenome® - the first clinical use of Phenomix's AI platform - to match patients with the treatments they're most likely to respond to, from GLP-1s to bariatric procedures.
The same platform keeps uncovering new insights, building the path to truly personalized, trait-based obesity care."
Natalie Ikeman, MPAS, PA-C
Obesity Medicine Specialist, Bhatti Gi Consultants
President MN Obesity Society
“Wait—I thought GLP-1s work for everyone? There’s something else?’ That’s a question I hear almost daily.
It’s incredibly rewarding to share the MyPhenome test with my patients. They appreciate knowing their treatment is informed by cutting-edge, data-driven insights—not trial and error.
I often tell them: if you had breast cancer, you wouldn’t want me guessing at the type or treatment. You’d expect a test to guide us. Your weight loss journey deserves that same level of precision and respect.”
Angela O'Neil, MD, FMCP-M
Co-Owner and CEO, Next Level Care
“As a Mayo Clinic–trained physician, I’m committed to applying evidence-based medicine in my integrative health practice. Yet so often, clinical judgment is the only tool we have—especially in obesity care. That’s why the MyPhenome test has been a game-changer.
For the first time, we have a precision medicine tool that removes the guesswork. It helps me and my patients understand which weight loss medication is most likely to work and what lifestyle interventions will be most effective based on their unique biology.”
