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Emotional Hunger in Obesity Predicted With Gene Risk Score

MedScape
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January 15, 2026
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Marylinn Larkin
A genetic risk score (GRS) predicted the risk emotional hunger (EH) in people with obesity and may enable testing of potential therapies.
Highlights:

“Emotional hunger is a real contributor to weight gain, and it’s often overlooked or misunderstood in today’s obesity care,” Andres Acosta, MD, PhD, cofounder of Phenomix Sciences and obesity expert at the Mayo Clinic, Rochester, Minnesota, said in a communication. “These early findings reinforce where the field is headed: precision obesity care that recognizes the biological, behavioral, and emotional components of the disease.”

A genetic risk score (GRS) predicted the risk emotional hunger (EH) in people with obesity and may enable testing of potential therapies. EH is defined as a high score (≥ 7) on the Hospital Anxiety and Depression Scale (HADS).

Read the full brief here.

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