Hungry Brain

Are you unable to feel full during a meal?

Satiation is the feeling of fullness and satisfaction that tells the brain when it’s time to stop eating. With a hungry brain, the brain is unable to determine when a meal is over, resulting in increased food consumption during a meal.

Satiation-related genes and/or low levels of certain metabolites predict the hungry brain obesity phenotype.

Along with limiting intake during meals, a weight loss intervention based on this classification works by stimulating hormones that relay fullness, which is shown to decrease food intake and body weight among individuals with this dominant phenotype.